Equity benchmarks as well as broader markets were flat in opening trade despite positive Asian cues.
The 30-share BSE Sensex was down 12.67 points at 31,801.55 and the 50-share NSE Nifty fell 7.90 points to 9,971.80.
About two shares advanced for every share falling on the BSE.
SPARC plunged 13 percent as Baclofen GRS did not meet primary end point in placebo controlled studies. Bacoflen is a muscle relaxer used to treat symptoms caused by Multiple Sclerosis.
TBZ, Titan Company, Sobha, Shakti Pumps, Speciality Restaurants and Jaiprakash Associates rallied 2-6 percent. Adani Enterprises, OBC and VA Tech were down 2-4 percent.
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